Jonathan Katz, M.D. , Scientist; Director of Neuromuscular Research at the Forbes Norris MDA/ALS Research and Treatment Center at CPMC

California Pacific CURRENTS: The online journal of CPMC Research Institute

Investigating treatments to delay the progression of motor neuron diseases

Research Overview

  • Dr. Katz studies amyotrophic lateral sclerosis (ALS), myasthenia gravis, neuromuscular diseases, pain management, peripheral neuropathy, poliomyelitis, radiculopathies, and spinal muscular atrophy.
  • He leads clinical trials of pharmacotherapies to slow the progression of ALS; device trials; a study of the NeuRX Diaphragm Pacing System to support patients with diaphragm weakness; and observational studies of factors affecting disease progression.
  • Dr. Katz and others at the Forbes Norris Center work with researchers at the University of California, San Diego, to study mutations in RNA binding proteins that cause neuronal dysfunction and death.
  • In 2014, Dr. Katz and colleagues at CPMC will collaborate with Cedars-Sinai Regenerative Medicine Institute on new stem cell and gene therapy techniques to treat ALS patients.
  • Dr. Katz is the Neuromuscular/Peripheral Nerve Lead for the Sutter Neuroscience Research Consortium.



Dr. Katz received his M.D. from Tulane University School of Medicine in New Orleans, Louisiana. He completed a residency at the University of Washington School of Medicine, and a fellowship at the University of Texas Southwestern Medical Center.


Publication Search


Levine TD, Miller RG, Bradley WG, Moore DH, Saperstein DS, Flynn LE, Katz JS, Forshew DA, Metcalf JS, Banack SA, Cox PA, Phase I clinical trial of safety of L-serine for ALS patients. Amyotroph Lateral Scler Frontotemporal Degener

Murphy J, Factor-Litvak P, Goetz R, Lomen-Hoerth C, Nagy PL, Hupf J, Singleton J, Woolley S, Andrews H, Heitzman D, Bedlack RS, Katz JS, Barohn RJ, Sorenson EJ, Oskarsson B, Fernandes Filho JA, Kasarskis EJ, Mozaffar T, Rollins YD, Nations SP, Swenson AJ, Koczon-Jaremko BA, Mitsumoto H, ALS COSMOS., Cognitive-behavioral screening reveals prevalent impairment in a large multicenter ALS cohort. Neurology

Jenkins JA, Sakamuri S, Katz JS, Forshew DA, Guion L, Moore D, Miller RG, Phrenic nerve conduction studies as a biomarker of respiratory insufficiency in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener

Jonathan Katz, M.D. , Scientist; Director of Neuromuscular Research at the Forbes Norris MDA/ALS Research and Treatment Center at CPMC
Primary Research Interests
  • Management of amyotrophic lateral sclerosis, myasthenia gravis, and other neuromuscular diseases

ALS Clinical Trials


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