Yount Lab

California Pacific CURRENTS: The online journal of CPMC Research Institute

genes that could contribute to the development post-traumatic stress disorder (PTSD)
Theoretical framework used to evaluated genes that could contribute to the development post-traumatic stress disorder (PTSD) based on their potential regulatory links between the hypothalamic-pituitary axis (HPA), autonomic nervous system (ANS), and inflammatory systems.
Overview

Even with standard-of-care therapy, many cancers become resistant to treatment and metastasize to surrounding healthy tissues. And although some chemotherapeutic agents can sensitize tumors to radiation therapy, these agents may have toxic side effects.

Our lab is focused on improving the treatment of glioblastoma (the most severe form of brain cancer) with camptothecin and other nontoxic herbal compounds used in Traditional Chinese Medicine. Using DNA microarray technologies, we are examining patterns of gene expression at many stages of tumor progression, to understand how herbs work from a modern genetic perspective.

We are evaluating physiologic and genetic changes associated with stress reduction and positive emotions, and the impact on disease outcomes.

Lead Investigator
Lab Members
Stephen Madamba, B.Sc.
Intern
Kenneth Rachlin, MSEE
Intern
Current Projects
  • Molecular and cellular biology of cancers
  • Mind-body approaches to health and well-being
  • Gene expression changes associated with stress