Gastrointestinal Disorders

California Pacific CURRENTS: The online journal of CPMC Research Institute

An underwater endoscopic view of the ileum

An underwater endoscopic view of the ileum (the third portion of the small intestine). Clinicians at CPMC were among the first endoscopists to investigate and clinically utilize many of the new micro-instruments for detecting and treating GI disorders.


 

Overview

Gastroenterology research at CPMC is conducted in interventional endoscopy, and neurogastroenterology/motility disorders.


Interventional endoscopy

Interventional endoscopy allows gastroenterologists to diagnose gastrointestinal (GI) disorders and perform surgical procedures. Drs. Yasser Bhat, Kenneth Binmoeller, and Janak Shah are at the forefront of clinical research as the first endoscopists to investigate and clinically utilize many of the new micro-instruments for detecting and treating GI disorders.  Examples of device clinical trials they have embarked upon include:  tissue sampling devices (brush, forceps and aspiration needles), needle and wire “knives,” injection catheters, clip, band, suture, and stent applicators, thermal coagulation probes, balloons and baskets, miniature endoscopes, and miniature ultrasound catheters.

Investigators

Yasser Bhat, M.D.
Kenneth Binmoeller, M.D.
 


Neurogastroenterology/motility disorders

Approximately 35 million Americans suffer from GI motility disorders including gastroparesis, irritable bowel syndrome, gastroesophageal reflux disease, and fecal incontinence. Motility disorders can involve any part of the GI tract (i.e., the esophagus, stomach, small intestines and colon). Dr. William Snape is the Principal Investigator of a nation-wide, federally funded study with the National Institutes of Diabetes and Digestion and Kidney Diseases.  The Gastroparesis Registry (GpR) is an observational study to clarify the epidemiology, natural history, clinical course, and outcomes of gastroparesis. The GpR will help inform the development of clinical trials and ancillary studies of the epidemiology, etiology, pathophysiology, and impact of gastroparesis. Clinical studies by Dr. Snape and his colleagues in the Center for Neurogastroenterology and Motility are already underway in this area, focusing on nausea, diabetes control, aspiration risk after extubation, and pharmacological interventions.

Investigator

William Snape, Jr., M.D.


Clinical Trials at CPMC

GI clinical trials

Related Programs at CPMC

Gastroenterology Services

Interventional Endoscopy Services